Research Overview

The Soniat lab focuses on determining mechanisms of genome maintenance. In particular, we use a combination of structural biology, single-molecule biophysics, biochemistry, and cell biology techniques to decipher how molecular machines involved in DNA repair and telomere maintenance protect genomic integrity. Ultimately, our goal is to increase our understanding of how genome instability contributes to aging and cancer and to aid in the development of new strategies to delay age-related diseases.

News and Events

November 2025- Ian Mawn presents his work at the 3rd Annual Genome Instability-Discovery to Personalized Medicine conference in Philadelphia.

September 2025- Katie Till is awarded the T32 training grant!

June 2025- Soniat lab published its first review article in DNA Repair.

June 2025- Katie Till joins the lab as a graduate student!

June 2024- Quynh Nguyen joins the lab as a graduate student!

June 2024- Zoë DeFazio joins the lab as a research technician!

November 2023- Tamim Al-Jubair joins the lab!

August 2023- Hemani departs the lab to attend Drexel’s Master's Program.

August 2023- Ian Mawn joins the lab as the lab’s first graduate student!

January 2023- Hemani Patel joins the lab as a research technician!

November 2022- The Soniat lab officially opens at Thomas Jefferson University.